The Single Best Strategy To Use For ceesdekker.net
The Single Best Strategy To Use For ceesdekker.net
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Using one-molecule optical and AFM imaging and power-spectroscopy methods, we search for to unravel the mechanistic aspects of the composition and dynamics of chromosomes. Our exploration passions consist of:
It was only from the 1990s nevertheless, when nanotechnology had Highly developed into a amount in which solitary molecules can be manipulated, that the primary experimental devices started to look.
[Laughs] ‘It was definitely a great risk! At some time, I had been very well informed that it could go Mistaken and that I could become significantly less prosperous, but I just overlooked that. Curiosity has often been my strongest driving drive. And by chance all of it worked out.’
A rhythmically pulsing leaf-spring DNA-origami nanoengine that drives a passive follower Mathias Centola
That is a aspiration of mine and we established to operate having a mouth watering dose of naivety. This really is something that will most likely generate spectacular leads to the for a longer period term, but that does not subject. You shouldn't only want to work about the thoughts of tomorrow, but additionally about the issues of the day soon after tomorrow.’
Microbiology has only been around to get a century, considering that we began to review micro-organisms additional very seriously. I assumed nanobiology was an correct term, simply because all molecular Organic suitable interactions occur within the nanoscale: a protein is a handful of nanometres in size, DNA is two nm thick.’
‘In the beginning we checked out Organic methods by using a Actual physical see and acted on The idea with the tools we knew. It took a couple of years in advance of we started off Operating a lot more on the massive Organic challenges. I then started to get in touch with it nanobiology, a expression that didn't exist at some time.
Dynamic ParB–DNA interactions initiate and sustain a partition condensate for bacterial chromosome segregation
‘Certainly, I realize people today had been amazed at the time. At the end of the nineties, After i was in my forties, I was Professor of Molecular Electronics and cees dekker I have to confess that it had become a little bit bored, I didn’t learn A lot anymore. The sphere went a lot more into the appliance facet, how you may combine nanotubes into Digital circuits.
Presently, we also understood that it ought to be attainable to work with an individual semiconducting carbon nanotube to generate a transistor — and we set out to make it. We stretched individual semiconducting nanotubes throughout metallic electrodes and made use of the fundamental silicon substrate being a gate electrode, developing the basic three-terminal structure of the discipline-impact transistor (Fig.
[14] In 2005 Dekker grew to become involved in Netherlands-extensive discussions about Intelligent Layout, a motion that he has given that Evidently distanced himself from. Dekker advocates that science and religion are certainly not in opposition but may be harmonized.
Quite a few new phenomena have been discovered, and he and his exploration group founded a leading posture With this area of investigate. Dekker and his investigation team uncovered new physics of nanotubes in addition to explored the feasibility of molecular electronics. In 1998, they ended up the initial to make a transistor depending on only one nanotube molecule.
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Supercoiling-dependent DNA binding: quantitative modeling and purposes to bulk and solitary-molecule experiments